Checked 2026-11-10. Independent clinical review has not been completed. WADAFUK is independent of WADA and does not provide medical advice or an individual anti-doping determination.
Prohibited at all times
2026 S4.4.4: prohibited at all times. Non-Specified. [1]
S4.4.4 · 2026 rules apply from 1 January 2026. Any 2027 material below concerns future rules from 1 January 2027; it is not current clearance.
Medical restrictions
EMA’s safety referral restricted trimetazidine to add-on symptomatic angina treatment when other treatment is inadequate or not tolerated. It removed the reviewed tinnitus, vertigo and visual indications. Movement disorders, including parkinsonism, and severe renal impairment are important warning or contraindication contexts. [2]
- This is an EU regulatory review, not a current worldwide label inventory.
Documented contamination case
In a 2024 tennis decision, independent testing supported trimetazidine contamination of a particular melatonin medicine, including opened and sealed same-batch containers. The decision accepted that product as the likely source in the individual case. This does not mean melatonin naturally contains trimetazidine or that other batches are contaminated. [3]
- One official case does not establish market prevalence or guarantee the same anti-doping outcome for another person.
What remains uncertain
- The draft’s other contamination and lomerizine-metabolism papers were not reappraised; their detailed findings are omitted. A measured concentration alone does not identify exposure source.
Check the sources.
These are concise editorial paraphrases of selected sources, not a systematic review or a reproduction of source tables. Access depth is shown for each reference; an abstract-only check cannot resolve details found only in a full paper.
- WADA 2026 Prohibited List ↗Accessed 2026-11-10 · Relevant official full-text sections opened
Printed pp. 3, 9–12: introduction, S3, S4 and S5 as applicable
- EMA trimetazidine referral ↗Accessed 2026-11-10 · Relevant document text opened
Relevant cited sections
- ITIA decision concerning Iga Swiatek, 27 November 2024 ↗Accessed 2026-11-10 · Relevant document text opened
Relevant cited sections
Check the current official WADA List and the relevant anti-doping authority for your sport, product, route and circumstances. Do not stop or change necessary treatment based on this page. Ask a qualified clinician about health decisions. Missing evidence does not establish safety.