INDEPENDENT ANTI-DOPING REFERENCE2026 · CHECKED 08 NOV 2027 PUBLISHED ↗
WADAFUK!?
Source-checked educational research

SR9009.

S4
Source-checked educational research

Checked 2026-11-10. Independent clinical review has not been completed. WADAFUK is independent of WADA and does not provide medical advice or an individual anti-doping determination.

REGULATORY SUMMARY2026 LIST

Prohibited at all times

2026 S4.4.1: prohibited at all times. Non-Specified. [1]

S4.4.1 · 2026 rules apply from 1 January 2026. Any 2027 material below concerns future rules from 1 January 2027; it is not current clearance.

EVIDENCE / 01

Mechanism and its limits

SR9009 is described in metabolic research as a REV-ERB ligand, but experiments in cells lacking both REV-ERB proteins still found effects on viability, metabolism and gene expression. Effects of SR9009 therefore cannot be used as specific proof of REV-ERB activity. [2]

Limits of this evidence
  • Cell and genetic-model evidence does not establish clinical benefit, a human dose or a human toxicity rate.
EVIDENCE / 02

Product evidence

A 2016 study verified SR9009 in one internet-sold product and investigated metabolism using human liver microsomes. This is direct evidence for that tested product, not a measure of current availability, purity or population exposure. [3]

Limits of this evidence
  • In-vitro metabolism is not a clinical efficacy or safety trial.
TRACEABILITY

Check the sources.

These are concise editorial paraphrases of selected sources, not a systematic review or a reproduction of source tables. Access depth is shown for each reference; an abstract-only check cannot resolve details found only in a full paper.

  1. WADA 2026 Prohibited List ↗Accessed 2026-11-10 · Relevant official full-text sections opened

    Printed pp. 3, 9–12: introduction, S3, S4 and S5 as applicable

  2. SR9009 has REV-ERB-independent effects on cell proliferation and metabolism ↗Accessed 2026-11-10 · Relevant document text opened

    Relevant cited sections

  3. In Vitro Metabolic Studies of REV-ERB Agonists SR9009 and SR9011 ↗Accessed 2026-11-10 · Relevant document text opened

    Relevant cited sections

Before acting on this information

Check the current official WADA List and the relevant anti-doping authority for your sport, product, route and circumstances. Do not stop or change necessary treatment based on this page. Ask a qualified clinician about health decisions. Missing evidence does not establish safety.

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