INDEPENDENT ANTI-DOPING REFERENCE2026 · CHECKED 08 NOV 2027 PUBLISHED ↗
WADAFUK!?
Source-checked educational research

GW501516.

S4
Source-checked educational research

Checked 2026-11-10. Independent clinical review has not been completed. WADAFUK is independent of WADA and does not provide medical advice or an individual anti-doping determination.

REGULATORY SUMMARY2026 LIST

Prohibited at all times

2026 S4.4.1: prohibited at all times. Non-Specified. [1]

S4.4.1 · 2026 rules apply from 1 January 2026. Any 2027 material below concerns future rules from 1 January 2027; it is not current clearance.

EVIDENCE / 01

Medical-development and safety context

GW501516, also named GW1516 in the List, is a PPAR-delta agonist. WADA’s 2013 alert described its development being stopped after serious preclinical toxicities. HSA’s 2017 warning discussed cancers in mouse and rat studies and an unestablished human safety profile. [2] [3]

Limits of this evidence
  • Historical official warnings support a serious hazard concern, not a numerical estimate of cancer risk in humans.
EVIDENCE / 02

Exposure evidence

The HSA alert documented online bodybuilding products labelled with cardarine/GW501516. This establishes historical marketing context; it should not be described as a new independent chemical assay of current products. [3]

Limits of this evidence
  • The separately cited internet-product assay could not be opened and its product-specific findings are not repeated here.
TRACEABILITY

Check the sources.

These are concise editorial paraphrases of selected sources, not a systematic review or a reproduction of source tables. Access depth is shown for each reference; an abstract-only check cannot resolve details found only in a full paper.

  1. WADA 2026 Prohibited List ↗Accessed 2026-11-10 · Relevant official full-text sections opened

    Printed pp. 3, 9–12: introduction, S3, S4 and S5 as applicable

  2. WADA alert concerning GW501516 (FIA-hosted original notice) ↗Accessed 2026-11-10 · Relevant document text opened

    Relevant cited sections

  3. HSA alert: bodybuilding products sold online contain harmful substances ↗Accessed 2026-11-10 · Relevant document text opened

    Relevant cited sections

Before acting on this information

Check the current official WADA List and the relevant anti-doping authority for your sport, product, route and circumstances. Do not stop or change necessary treatment based on this page. Ask a qualified clinician about health decisions. Missing evidence does not establish safety.

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