INDEPENDENT ANTI-DOPING REFERENCE2026 · CHECKED 08 NOV 2027 PUBLISHED ↗
WADAFUK!?
Source-checked educational research

Domagrozumab.

S4
Source-checked educational research

Checked 2026-11-10. Independent clinical review has not been completed. WADAFUK is independent of WADA and does not provide medical advice or an individual anti-doping determination.

REGULATORY SUMMARY2026 LIST

Prohibited at all times

2026 S4.3: prohibited at all times. Non-Specified. [1]

S4.3 · 2026 rules apply from 1 January 2026. Any 2027 material below concerns future rules from 1 January 2027; it is not current clearance.

EVIDENCE / 01

Clinical research

A randomized phase 2 trial enrolled 120 ambulatory boys aged six to under sixteen with Duchenne muscular dystrophy. Domagrozumab did not significantly improve the four-stair-climb endpoint or the reported secondary clinical endpoints compared with placebo. Most reported adverse events were mild and not considered treatment-related. [2]

Limits of this evidence
  • Abstract reviewed; findings apply to this DMD trial, not healthy athletes. No general safety or efficacy claim follows from tolerability in this setting.

What remains uncertain

  • Current therapeutic authorization and consumer-product exposure were not established. The linked publication lists an erratum; detailed numerical efficacy claims are omitted.
TRACEABILITY

Check the sources.

These are concise editorial paraphrases of selected sources, not a systematic review or a reproduction of source tables. Access depth is shown for each reference; an abstract-only check cannot resolve details found only in a full paper.

  1. WADA 2026 Prohibited List ↗Accessed 2026-11-10 · Relevant official full-text sections opened

    Printed pp. 3, 9–12: introduction, S3, S4 and S5 as applicable

  2. Randomized phase 2 domagrozumab trial in DMD ↗Accessed 2026-11-10 · Primary-study abstract and metadata

    Abstract and bibliographic record

Before acting on this information

Check the current official WADA List and the relevant anti-doping authority for your sport, product, route and circumstances. Do not stop or change necessary treatment based on this page. Ask a qualified clinician about health decisions. Missing evidence does not establish safety.

Something wrong? Prepare a correction draft ↗