INDEPENDENT ANTI-DOPING REFERENCE2026 · CHECKED 08 NOV 2027 PUBLISHED ↗
WADAFUK!?
Source-checked educational research

Brinzolamide.

S5
Source-checked educational research

Checked 2026-11-10. Independent clinical review has not been completed. WADAFUK is independent of WADA and does not provide medical advice or an individual anti-doping determination.

REGULATORY SUMMARY2026 LIST

Conditional restriction

WADA 2026: topical eye administration is excepted from S5. Other routes do not receive that exception. The future 2027 List retains it. [1] [2]

2026 and 2027 List, S5, printed p.12; introductory definitions p.3 · 2026 rules apply from 1 January 2026. Any 2027 material below concerns future rules from 1 January 2027; it is not current clearance.

EVIDENCE / 01

Medical and pharmacological context

US ophthalmic-suspension labeling describes a carbonic anhydrase inhibitor for elevated eye pressure in ocular hypertension or open-angle glaucoma. The drug can be systemically absorbed after eye administration. [3]

Limits of this evidence
  • The cited country-specific product information does not establish worldwide authorization or current supply.
EVIDENCE / 02

Health concerns

Warnings include sulfonamide hypersensitivity and corneal edema in susceptible patients. The reviewed label does not recommend use in severe kidney impairment. [3]

Limits of this evidence
  • Selected warnings, not a complete contraindication or interaction list. Patient-label evidence does not establish athlete safety.
EVIDENCE / 03

Combination eye drops

The eye-route exception does not clear an entire combination product. WADA separately restricts beta-blocker eye drops in particular sports. [4]

What remains uncertain

  • Educational synthesis only; not individualized medical advice, a TUE decision or a sanction prediction.
TRACEABILITY

Check the sources.

These are concise editorial paraphrases of selected sources, not a systematic review or a reproduction of source tables. Access depth is shown for each reference; an abstract-only check cannot resolve details found only in a full paper.

  1. WADA 2026 Prohibited List ↗Accessed 2026-11-10 · relevant full-text sections independently opened and inspected

    Introduction p.3 · S5 p.12

  2. WADA 2027 Prohibited List, 4 November revision ↗Accessed 2026-11-10 · relevant full-text sections independently opened and inspected · FUTURE 2027 SOURCE

    Introduction p.3 · S5 p.12

  3. DailyMed brinzolamide ophthalmic suspension ↗Accessed 2026-11-10 · relevant full-text sections independently opened and inspected

    Indications; clinical pharmacology or SmPC sections 4.1 and 5.1 · Warnings, precautions and adverse reactions

  4. WADA Prohibited List and FAQs ↗Accessed 2026-11-10 · relevant full-text sections independently opened and inspected

    FAQ: eye drops containing beta-blockers · FAQ: intravenous iron dextran · WADA mannitol FAQ; Bronchitol indication and bronchospasm warning

Before acting on this information

Check the current official WADA List and the relevant anti-doping authority for your sport, product, route and circumstances. Do not stop or change necessary treatment based on this page. Ask a qualified clinician about health decisions. Missing evidence does not establish safety.

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