Checked 2026-11-10. Independent clinical review has not been completed. WADAFUK is independent of WADA and does not provide medical advice or an individual anti-doping determination.
Prohibited at all times
2026 S4.4.1: prohibited at all times. Non-Specified. [1]
S4.4.1 · 2026 rules apply from 1 January 2026. Any 2027 material below concerns future rules from 1 January 2027; it is not current clearance.
Identity and mechanism
The NCI acadesine entry describes AICA riboside, a nucleoside analogue converted inside cells to ZMP, which mimics AMP and can activate AMPK pathways. The riboside and the phosphorylated intracellular product are different chemical forms; abbreviation-only records should not silently merge them. [2]
- This dictionary supports identity and mechanism, not current therapeutic approval or clinical efficacy.
What remains uncertain
- The cited human leukemia study and its full-text alternative could not be retrieved. Trial results, dosing, and safety claims from the draft were omitted; no current marketing authorization was established.
Check the sources.
These are concise editorial paraphrases of selected sources, not a systematic review or a reproduction of source tables. Access depth is shown for each reference; an abstract-only check cannot resolve details found only in a full paper.
- WADA 2026 Prohibited List ↗Accessed 2026-11-10 · Relevant official full-text sections opened
Printed pp. 3, 9–12: introduction, S3, S4 and S5 as applicable
- NCI Drug Dictionary: acadesine ↗Accessed 2026-11-10 · Relevant document text opened
Relevant cited sections
Check the current official WADA List and the relevant anti-doping authority for your sport, product, route and circumstances. Do not stop or change necessary treatment based on this page. Ask a qualified clinician about health decisions. Missing evidence does not establish safety.